Treatment of stiff person syndrome with rituximab.
نویسندگان
چکیده
This case report is about the novel use of the anti-CD20 antibody, rituximab, in the treatment of a 41 year old woman with stiff person syndrome. She was admitted to hospital as an emergency with prolonged and painful extensor spasms affecting the neck and back, arms, and legs. The disease had progressed despite a favourable initial response to conventional treatment with intravenous immunoglobulin and cytotoxics. Treatment with rituximab induced a lasting clinical remission.
منابع مشابه
Childhood Stiff-Person Syndrome Improved with Rituximab
INTRODUCTION Stiff-person syndrome (SPS) is manifested by fluctuating rigidity of axial musculature with painful episodic spasms due to simultaneous co-contraction of agonist and antagonist muscles. We present a case report and video illustrating response to treatment with rituximab. MATERIALS AND METHODS Case description and video are provided. A literature search for other reports of treatm...
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عنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 76 7 شماره
صفحات -
تاریخ انتشار 2005